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Centre for Bio-Engineering (Center)
Faculty of Engineering Kragujevac
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Centre for Bio-Engineering (CBI) was founded in June 2006 at initiative of professors Miloš Kojić and Nenad Filipović. The first and current manager is Professor Nenad Filipović. The Centre was established as the result of a number of international and national scientific projects and international papers in the area of bio-engineering. The Elaborate and the Decision on Establishment of CBI defines the rooms used by the Centre (room C-22) as well as the equipment purchased from the projects in bio-engineering area.


• Simulation of cardio-vascular systems 
• Simulation of respiratory systems 
• Simulation of muscle functions  
• Sport bio-mechanics  
• Medicines transport, nanotechnology  
• Tumour growth prediction  

Name email Host institution
true Filipović Nenad fica@kg.ac.rs Faculty of Engineering Kragujevac
Đukić Tijana Faculty of Engineering Kragujevac
Isailović Velibor Faculty of Engineering Kragujevac
Mijailović Nikola Faculty of Engineering Kragujevac
Milošević Žarko Faculty of Engineering Kragujevac
Nikolić Dalibor Faculty of Engineering Kragujevac
Obradović Milica Faculty of Engineering Kragujevac
Petrović Dejan Faculty of Engineering Kragujevac
Radović Miloš Faculty of Engineering Kragujevac
Saveljić Igor Faculty of Engineering Kragujevac
Vukićević Arso Faculty of Engineering Kragujevac
Vulović Radun Faculty of Engineering Kragujevac
Živanović Marko Faculty of Engineering Kragujevac

• More than 400 papers were published in international journals and over 350 papers at international and national conferences  
• Software for simulation of blood flow through blood vessels was developed 
• Software for simulation of air flow in alveoli was developed 
• Software for noise analysis from blind Doppler was developed  
• Software for simulation of spinal column load was developed 

Project title Project type
Razvoj metoda i softvera za numerička i eksperimentalna istraživanja iz oblasti biomedicinskih nauka National
Razvoj metoda, softvera i uređaja za oblast biomehanike i bioinženjeringa National
Transport biološki aktivnih molekula u fiziološkim membranama National
Razvoj kompjuterskih modela i softvera za modeliranje i simulacije iz oblasti opšteg i biomedicinskog inženjeringa National
Metode modeliranja biomehaničkih sistema sa primenom u medicini, National
Razvoj softvera i hardvera iz oblasti bioinženjeringa sa primenom u kliničkoj praksi, National
Development of an Anatomical Model for the Simulation of Excitation Propagation And Cardiac Biomechanics International
Integracija otkrivanja zakonitosti podataka i složenog kompjuterskog modeliranja bolesti koronarnih arterija International
Specifični kompjuterski model koronarnih arterija kod pacijenta i predviđanje nastanka i razvoja arterosklerotičkog plaka International
Multi-level patient-specific artery and atherogenesis model for outcome prediction, decision support treatment, and virtual hand-on training International
Multi-level protection of materials for vehicles by “SMART” nanocontainers International
Razvoj metoda i softvera za modeliranje elektromagnetnog polja prilikom funkcionalne elektrostimulacije na ruci International
Razvoj anatomskog modela za simulaciju širenja pobuda u kompleksnom sistemu elektro-kardio-biomehanike International
South-Eastern European Grid-enabled eInfrastructure Development 2 International
New cardiovascular planning and diagnostic tool for coronary arteries in BSEC countries using computational simulation International
Integracija otkrivanja zakonitosti podataka i složenog kompjuterskog modeliranja bolesti koronarnih arterija International
  1. Nenad Filipovic, Zhongzhao Teng, Milos Radovic, Igor Saveljic, Dimitris Fotiadis and Oberdan Parodi, Computer simulation of three dimensional plaque formation and progression in the carotid artery, Medical & Biological Engineering & Computing, DOI: 10.1007/s11517-012-1031-4, (2013)
  2. Parodi O., Exarchos T., Marraccini P., Vozzi F., Milosevic Z., Nikolic D., Sakellarios A., Siogkas P., Fotiadis D.I., Filipovic N., Patient-specific prediction of coronary plaque growth from CTA angiography: a multiscale model for plaque formation and progression, IEEE Transaction on Information Technology in Biomedicine, Vol. 16(5), pp. 952-965, (2012)
  3. Filipovic N., Isailovic V., Djukic T., Ferrari M., Kojic M., Multiscale Modeling of Circular and Elliptical Particles in Laminar Shear Flow, IEEE transactions on biomedical engineering, Vol. 59(1), pp. 50-53.DOI: 10.1109/TBME.2011.2166264, (2012)
  4. Filipovic N., Rosic M., Tanaskovic I., Milosevic Z., Nikolic D., Zdravkovic N., Peulic A., Fotiadis D., Parodi O., ARTreat project: Three-dimensional Numerical Simulation of Plaque Formation and Development in the Arteries, IEEE Trans Inf Technol Biomed, Vol. 16(2), pp. 272-278, (2012)
  5. Dimkic M., Rankovic V., Filipovic N., Stojanovic B., Isailovic V., Pusic M., Investigation of the M., Modeling of radial well lateral screens using 1D finite elements,  Journal of Hydroinformatics, IWA Publishing.DOI:10.2166/hydro.2012.008, (2012)
  6. Oberdan Parodi, Themis Exarchos, Paolo Marraccini, Federico Vozzi, Zarko Milosevic, Dalibor Nikolic, Antonis Sakellarios, Panagiotis Siogkas, Dimitris I. Fotiadis, Nenad Filipovic, Patient-specific prediction of coronary plaque growth from CTA angiography: a multiscale model for plaque formation and progression, IEEE Transactions on Information Technology and Applications in Biomedicine (in press)
  7. Siogkas, P.,   Sakellarios, A.,   Exarchos, T. P.,   Athanasiou, L.,   Karvounis, E.,   Stefanou, K.,   Fotiou, E.,   Fotiadis, D. I.;   Naka, K. K.;   Michalis, L. K.;   Filipovic, N.;   Parodi, O.;  Multiscale - Patient-Specific Artery and Atherogenesis Models, IEEE Trans Biomed Eng. 2011 Dec; 58(12):3464-8.
  8. Z. Bosnić, P. Vračar, M. Radović, G. Devedžić, N. Filipović, and Igor Kononenko, Mining Data from Hemodynamic Simulations for Generating Prediction and Explanation Models, Transactions on Information Technology in Biomedicine, in press, DOI 10.1109/TITB.2011.2164546.
  9. Filipovic NIsailovic VDjukic T, Ferrari M, Kojic M., Multi-scale modeling of circular and elliptical particles in laminar shear flow, IEEE Trans Biomed Eng. PMID: 21878403, (2011)
  10. Filipovic NRosic MTanaskovic IMilosevic ZNikolic DZdravkovic NPeulic A. Fotiadis D, Parodi O, ARTreat project: Three-dimensional Numerical Simulation of Plaque Formation and Development in the Arteries, IEEE Trans Inf Technol Biomed. PMID: 21937352 (2011)
  11. Markovic Zoran S,  Dimitric-Markovic Jasmina M,  Milenkovic Dejan,  Filipovic N, Mechanistic study of the structure-activity relationship for the free radical scavenging activity of baicalein, JOURNAL OF MOLECULAR MODELING, vol. 17 br. 10, str. 2575-2584, (2011)
  12. Dimkic M,  Pusic M,  Vidovic D,  Isailovic V,  Majkic B  Filipovic N, Numerical Model Assessment of Radial-Well Aging, JOURNAL OF COMPUTING IN CIVIL ENGINEERING, vol. 25 1, 43-49, (2011)
  13. Lee G, Filipovic N,  Lin M,  Gibney B  Simpson D,  Konerding M,  Tsuda A, Mentzer S, Intravascular Pillars and Pruning in the Extraembryonic Vessels of Chick Embryos  DEVELOPMENTAL DYNAMICS,vol. 240 br. 6, str. 1335-1343, (2011)
  14. Dimitric-Markovic M,  Markovic Z.  Brdaric T.   Filipovic N. Comparative spectroscopic and mechanistic study of chelation properties of fisetin with iron in aqueous buffered solutions. Implications on in vitro antioxidant activity, DALTON TRANSACTIONS, vol. 40, 17, 4560-4571, (2011).
  15. Filipovic  N. and H. Schima,  Numerical simulation of the flow field within the aortic arch during cardiac assist, Artifical Organs, 35, 4,  73–83, (2011)
  16. Kojic N., A. Huang, E. Chung, M.Ivanovic, N.Filipovic, M. Kojic, and D. Tschumperlin, A 3-D model of ligand transport in a deforming extracellular space, Biophysical Journal, Dec 1;99(11):3517-25.(2010).
  17. Filipovic N., M. Ivanovic, D. Krstajic and M.Kojic, Hemodynamic Flow Modeling through an Abdominal Aorta  Aneurysm Using Data Mining Tools, IEEE - Transactions on Information Technology in Biomedicine, Mar;15(2):189-94 (2011)
  18. Filipovic, N., M. Kojic, M. Ferrari, Dissipative Particle Dynamics Simulation of Circular and Elliptical Particles Motion in 2D Laminar Shear Flow, Microfluidics and Nanofluidics,  10, 5, 1127-1134, 2010.
  19. Lee G., Filipovic, N., et al, Blood flow shapes intravascular pillar geometry in the chick chorioallantoic membrane, Journal of Angiogenesis Research, 2:11, 2010
  20. Filipovic, N.,  A. Cvetkovic, V. Isailovic, Z. Matovic, M. Rosic and M. Kojic, Computer simulation of flow and mixing at the duodenal stump after gastric resection, World Journal of Gastroentrology, 15 (16), 1990-1998, 2009
  21. Filipovic, N., AkiraTsuda, Grace S. Lee, Lino F. Miele, Miao Lin, Moritz A., Konerding, and Steven J. Mentzer, Computational Flow Dynamics in a Geometric Model of Intussusceptive Angiogenesis, Microvascular Research Dec;78(3):286-93, 2009.
  22. Tsuda, A., Filipovic, N.,  Haberthür, D., Dickie, R.,  Matsui, Y., Stampanoni, M. and SchittnyJ.C., Finite element 3D reconstruction of the pulmonary acinus imaged by synchrotron X-ray tomography, J Appl Physiol 105: 964-976, 2008
  23. Filipovic, N., M. Ivanovic, M. Kojic, A comparative numerical study between dissipative particle dynamics (DPD) and smooth particle dynamics (SPH) when applied to simple unsteady flows, Microfluidics and Nanofluidics, 1613-4982, 2008.
  24. Filipovic, N., Haber,  S., Kojic, M., Tsuda, A., Dissipative particle dynamics simulation of flow generated by two rotating concentric cylinders: II. Lateral dissipative and random forces, J. Phys. D: Appl. Phys. 41 035504 (6pp)   doi:10.1088/0022-3727/41/3/035504, 2008
  25. Filipovic, N., Kojic, M., Tsuda, A., Мodeling thrombosis using dissipative particle dynamics method, Phil Trans Royal, A 366(1879), 2008
  26. Kojic, M., Filipovic, N., Tsuda, A., A mesoscopic bridging scale method for fluids and coupling dissipative particle dynamics with continuum finite element method, Comput. Methods Appl. Mech. Engrg. 197, 821–833, 2008.
  27. Filipovic, N., Ravnic, D.J. Kojic, M., Mentzer, S.J., Haber, S. Tsuda, A., Interactions of Blood Cell Constituents: Experimental investigation and Computational Modeling by Discrete Particle Dynamics Algorithm, Microvascular Research, 75, 279-284, 2008.
  28. Haber S., Filipovic N., Kojic M. and Tsuda A.Dissipative Particle Dynamics Simulation of flow generated by two rotating concentric cylinders. Part I: Boundary conditions, Phys. Rev. E. 74, pp.1-8, 2006.
  29. Filipovic N., Mijailovic S., Tsuda A. and Kojic M. An Implicit Algorithm Within The Arbitrary Lagrangian-Eulerian Formulation for Solving Incompressible Fluid Flow With Large Boundary Motions, Comp. Meth. Appl. Mech. Eng. 195: pp.6347-6361, 2006.
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